Kinetics of Cyclophosphamide and Ifosfamide Degradation from Aqueous System via TiO2 Assisted Photocatalysis

Abstract

Cyclophosphamide (CP) - N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide and ifosfamide (IF) - N,3-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amide 2-oxide degradation under UV-Vis/TiO2 photocatalysis was studied in the following experimental conditions: photocatalyst dose = 100 – 800 mg/L; irradiation time = 30-360 min; initial pollutant concentration = 1 – 50 mg/L. CP and IF degradation via TiO photocatalysis was found to obey Langmuir – Hinshelwood model and pollutants degradation rate constants: 5.89 x 10-6 M min-1 (CP); 4.86 x 10-6 M min-1 (IF) and pollutants adsorption – desorption on TiO2 particles equilibrium constants: 5637 M-1 (CP); 4930 M-1 (IF) were calculated.