Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1357
Title: Possible pathway for ifosfamide degradation via Fe-TiO2 assisted photo catalysis
Authors: Constantin, Lucian Alexandru
Constantin, Mirela Alina
Nitoi, Ines
Chiriac, Laura Florentina
Pascu, Luoana Florentina
Galaon, Toma
Keywords: Fe doped TiO2
Ifosfamide
Heterogeneous photo catalysis
Degradation intermediates
Issue Date: 2018
Publisher: SYSCOM 18 SRL
Abstract: Ifosfamide (IF) degradation from aqueous system via UV-Vis Fe-TiO2 system was studied for a photo catalyst dose of 200 mg/L and an irradiation time up to 240 min. IF degradation efficiency was monitored via Liquid Chromatography-Mass Spectrometry technique (LC-MS). Experimental photocatalytic tests were performed both in the absence and presence of 2-propanol and F- radicals’ scavengers and the results proved that IF degradation occurs most likely in the bulk solution. Experimental results showed that degradation efficiencies for IF varied between 39.52% in the presence of 2-propanol and 70.70% in the scavengers’ absence. Six degradation intermediates were identified using the same LC-MS technique and a three stage degradation pathway was proposed based on both available literature data and evolution of degradation intermediates peaks.
Description: Revista de Chimie (Bucharest), vol. 69, no. 11, pag. 4134-4137, 2018
URI: http://hdl.handle.net/123456789/1357
ISSN: 0034-7752
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