Influences of several factors on the photolysis of epirubicin

Abstract

Epirubicin is the 4`-epimer of doxorubicin and is a member of the antracycline class of antibiotics. Epirubicin produces less side effects that doxorubicin and so it can be used in higher doses. This has been used in the treatment of breast, gastric, ovarian, colorectal carcinomas. Prior studies have shown that the stability of drug may be influenced by environmental factors relative and air humidity. The stability of epirubicin is important to be investigate both in the solutions and in solid phase.