Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/825
Title: The obtaining of high sensitivity and specificity transducer media for sensors specialized in biological toxin detection
Authors: Petrea, Nicoleta
Zamora Iordache, Petrisor
Somoghi, Vasile
Savu, Ion
Muresan, Mihaela
Petre, Razvan
Rece, Liliana
Lungu, Rodica Mihaela
Pretorian, Andrada
Mitru, Georgeta
Dionezie, Bojin
Savu, Bogdan
Mutihac, Lucia
Kim, Lidia
Ordeanu, Viorel
Keywords: Biochemical sensors
Reversed mycelia
Biochemical activation
Ricin
Fe3O4
Confocal microscopy
Issue Date: 2009
Publisher: National Institute R&D Materials Physics
Abstract: This paper presents the experimental results obtained as a result of the testing on castor of a new type of nanocomposite superparamagnetic material. The purpose of the biochemical fixing tests was to obtain information concerning the characteristics of the biochemical fixing: efficiency, mechanisms, etc. The tested nanocomposite structure represents a new nanocomposite material, of the (ECH)nβ-{Fe3O4-n[SiO1.5γ-(CH2)3(NH2)](NH2)nδ}-(GL)nε type [(ECH)-npa-(GL) → coated and polyvalently biochemically activated nanoparticles {n[SiO1.5γ-(CH2)3(NH2)](NH2)nδ = coating layer; (NH2)nδ,-NH2= shallow layer of amino groups (GL)nε= shallow molecular layer of glutaraldehyde (ECH)nβ= shallow molecular layer of epiclorhydrine}. In order to obtain eloquent information concerning the -NH2, =NH, -NH3OH, -SH, -OH, -S-S- haptene distribution, the magnetite nanoparticles were synthetised through the reversed mycelia method. Another main objective was to verify the concept of dynamic and in real time ’undestructive biochemical fixing’. The veridicity of this concept offers the possibility of applying npa-BC in thin sensitive layers, on interfaceable supports of the following types: thin oxyde and metallic layers, electronic transducers, interfaces amplifying the electric signal, etc.
Description: Digest Journal of Nanomaterials and Biostructures Volume 4 Issue 4
URI: http://hdl.handle.net/123456789/825
ISSN: 1842-3582
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