Petre, JanaJanaPetre2017-04-042017-04-0420092014http://hdl.handle.net/123456789/712Program NUCLEU PN 09 13 01 09Methods for simultaneous determination of pharmaceutical residues from different structural and therapeutic classes in wastewater and surface water have been developed. These are: analgesics / antiinflammatories (acetaminophen, ketoprofen, naproxen, indomethacin, diclofenac, ibuprofen), antibiotics (erythromycin, azithromycin, sulfamethoxazole trimethoprim, norfloxacin, ofloxacin, ciprofloxacin, ampicillin, amoxicillin, penicillin V, penicillin G, oxacillin, cephalexin, clarithromycin, roxithromycin), diuretics (furosemide, hydrochlorothiazide), antiseptic (triclosan, triclocarban), carbamazepine, caffeine, gemfibrozil. The methods are based on solid-phase extraction techniques, separation by high-performance liquid chromatography, electrospray ionization and detection, confirmation and quantification by tandem mass spectrometry (SPE-HPLC-ESI-MS/MS). The developed methods were used to control the pollution with these pharmaceutical residues of influent and effluent of urban stations for wastewater treatment, as well as to evaluate the receiving surface water contamination.en-USPharmaceutical residuesWastewaterRisk assessmentProject