Air pollution is a serious problem in many heavily populated and industrialized areas in the world. It affects vegetation, and also human health. The diversification of emission sources, among them vehicles, industrial processes, waste burnings and fuel storage, create zones with different species and concentrations of air pollutants. In this paper was studied the excessive accumulation of toxic metals such as Al, Cr, Ni, Zn, Pb in vegetation as a risk factor for ecosystem and also for human health. The purpose of the study was to establish an optimal method of determination for toxic elements accumulation in leaves, using Inductively Coupled Plasma Mass Spectrometry (ICP-MS). These results made to suppose that, visible and analyzed responses of in in-situ exposed bio monitors compared with heavy metal accumulation depended on the atmospheric situation during the period of exposure, which could assess the efficiency of biomonitoring programs in the region. The advantage of this study consists in new and appropriate approach using a friendly methodology for air monitoring and favoring the development of a circular and sustainable economy.