Study of bacteria resistance mechanisms in response to a stress induced by pharmaceuticals compounds

Three pharmaceutical compounds (Trimethoprim, Carbamazepine and Benzethonium chloride) were investigated to unveil possible toxic effects on two bacterial strains (Citrobacter freundii and Comamonas testosteroni). The pharmaceutical compounds stress triggered a bacterial defence mechanism which was evaluated at transcriptional and translational levels. In this study, potential bacterial biomarkers induced by the
pharmaceutical stress were unraveled.